Non sedating benadryl alternative

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Antihistamines are included in over-the counter cold and cough preparations even though there is little evidence of benefit and unwanted side effects such as sedation can be risky.

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Antihistamines are drugs which block the receptors so that the histamine messages are not received.

H1 receptors tend to produce the symptoms already listed and activate allergic reactions.

H2 receptors tend to act as negative feedback receptors and turn the allergic reaction off.

Loratadine (Claritin) 10 mg daily 1-2 hours 24 hours Cetirizine (Reactine) 10 mg daily 1-2 hours 24 hours Fexofenadine ( Allergra) * Seldane and Hismanal have been withdrawn from the US market and placed on prescription drug status in Canada because of rare fatal ventricular arrythmias reported with larger than normal doses, in patients with liver disease and when the drugs were administered along with erythromycin, ketoconazole and other drugs. Doxepin is a tricyclic antidepressant with marked antihistamine activity. There is drug interaction with MAOIs, and can cause cardiac arrhythmia.

Seldane has been replaced by Fexofenadine ( Allergra), a metabolite of terfenadine with no know cardiac effects. Dosage : 10 mg The H2 receptor blocker, cimetidine, first marketed as "Tagamet", joins Valium as one of the best-selling drugs of all time. This acid reduction helps to prevent and to heal peptic ulcers.

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